A report on the state of the AIDS epidemic as of 2016 by UNAIDS. The report indicates that a lot has been done to fight the AIDS scourge but a a lot still needs to be done if the world is to effectively eliminate the epidemic by 2030. How to reach this bold target within the Sustainable Development Goals is the central question facing the United Nations General Assembly High-Level Meeting on Ending AIDS, to be held from 8 to 10 June 2016. The extraordinary accomplishments of the last 15 years have inspired global confidence that this target can be achieved. UNAIDS recommends a Fast-Track approach: substantially increasing and front loading investment over the next five years to accelerate scale-up and establish the momentum required to overcome within 15 years one of the greatest public health challenges in this generation. The latest UNAIDS data, covering 160 countries, demonstrate both the enormous gains already made and what can be achieved in the coming years through this approach.