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Technical Update on HIV Incidence Assays for Surveillance and Monitoring Purposes

Publication year: 
2015
Corporate author: 
UNAIDS, WHO
Publication details: 
Geneva, WHO, 2015
Abstract:

This document is intended for epidemiologists, statisticians and laboratory
technicians responsible for the use of HIV incidence assays for surveillance and
epidemic monitoring purposes. People that are not technical experts in this field
may prefer to first read the UNAIDS/WHO Working Group on Global HIV/AIDS
and STI Surveillance published guidelines on When and How to Use Assays for
Recent Infection to Estimate HIV Incidence at a Population Level [1] for a basic
introduction to this topic.

The purpose of this technical update is to summarize recent findings and offer new
recommendations in the field of HIV incidence assays. This update is based on
recently published literature and presentations at the WHO HIV Incidence Assay
Working Group Meeting in October 2014 in Barcelona, Spain. This meeting was
sponsored by the World Health Organization (WHO), the US Government’s
Centers for Disease Control and Prevention (CDC), the Consortium for the
Evaluation and Performance of HIV Incidence (CEPHIA) and the Joint United
Nations Programme on HIV/AIDS (UNAIDS). A detailed meeting report is
available at
http://www.who.int/diagnostics_laboratory/links/hiv_incidence_assay/en/.

This document is divided into four sections. The first provides a brief summary of
where we are at in the development and use of HIV incidence assays for
surveillance and epidemic monitoring. The second section summarizes recent
findings from the literature and the October 2014 WHO HIV Incidence Assay
Working Group Meeting in Barcelona, Spain. The third section provides a
summary of key recommendations from the meeting report reflecting consensus
among participants on key topics. The fourth section describes future directions
and research needs arising from the meeting.

This technical update supersedes the previous WHO/UNAIDS technical update on
HIV incidence assays for surveillance and epidemic monitoring published on 30
May 2013.