Skip navigation.

When and How to Use Assays for Recent Infection to Estimate HIV Incidence at a Population Level

Publication year: 
Corporate author: 
Publication details: 
Geneva, WHO, 2011

This guideline document first briefly reviews the public health importance of estimating the HIV incidence in populations, and the various methods that have been used for this purpose. It then provides guidance on the way in which laboratory tests for recent HIV infection may be used to estimate HIV incidence in populations, particularly with regard to sampling designs, sample size and the statistical analyses that should be employed.

This document has been prepared by the World Health Organization (WHO), through its Technical Working Group on HIV Incidence Assays that was established in 2008. The guidance is specifically aimed at those responsible for the funding, implementation or evaluation of HIV prevention programmes rather than the specialist in epidemiological or laboratory diagnostic methods; although a general understanding of these two subject areas is assumed of the readership.