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Guidelines on Post-Exposure Prophylaxis for HIV and the Use of Co-Trimoxazole Prophylaxis for HIV-Related Infections Among, Adults, Adolescents and Children: Recommendations for a Public Health Approach

Publication year: 
Corporate author: 
World Health Organization (WHO)
Publication details: 
Geneva, WHO, 2014

These guidelines provide new recommendations and updates to previous recommendations outlined in Chapter 5 (ARV drugs for HIV prevention) and Chapter 8 (Managing common coinfections and comorbidities) of the 2013 consolidated ARV guidelines, and following the similar structure of the 2013 ARV guidelines, these
recommendations are organized along the continuum of care. The guidelines reflect important advances in the use of ARV drugs to prevent HIV with more simplified approaches to post-exposure prophylaxis and simplifying the indications on the use of co-trimoxazole to prevent opportunistic infections, bacterial infections and malaria. Consistent with previous WHO guidelines, the guidelines are based on a public health approach that considers feasibility and effectiveness across a variety of settings. The key principles of availability, affordability, acceptability, accessibility and quality have been considered in producing these recommendations.